Course Descriptions

Genetics

Professors D. Bell-Pedersen, M. J. Benedik, D. L. Busbee, V. M. Cassone, B. P. Chowdhary, N. D. Cohen, J. N. Derr, M. B. Dickman, D. J. Ebbole, A. C. R. Ficht, T. A. Ficht, R. H. Finnell, J. R. Gold, C. F. Gonzalez, I. F. Greenbaum, T. C. Hall, P. E. Hardin, J. S. Johnston, C. M. Kenerley, J. L. Leibowitz, T. D. McKnight, C. W. Magill, J. E. Mullet, W. D. Park, D. O. Peterson, B. B. Riley, M. Sachs, S. H. Safe, P. B. Samollow, F. Schroeder, D. E. Shippen, L. C. Skow, C. W. Smith, T. E. Spencer, D. M. Stelly, R. D. Wells, C. J. Welsh, M. E. Westhusin, J. R. Wild, J. E. Womack, H. Zhang; Associate Professors R. Aramayo, L. R. Bernstein, M. Bryk, C. J. Coates, J. Cruz-Reyes, S. Datta, J. W. Erickson, R. Fan, L. R. Garcia, C. A. Gill, J. Gould, A. D. Herring, J. C. Hu, N. H. Ing, G. M. Kapler, S. R. King, K. V. Krutovsky, G. R. Kunkel, C. Loopstra, W. J. Murphy, V. M. Panin, S. L. Payne, A. E. Pepper, M. Polymenis, W. W. Porter, G. Rosenthal, J. E. Samuel, D. A. Siegele, H. H. Wilkinson, G. Zhu, K. Zhu-Salzman; Assistant Professors C. D. Allred, H. Andrews-Polymenis, P. de Figueiredo, R. Lints, M. Liu, C. R. Long, K. A. Maggert, M. Mateos, B. D. Perkins, H. Qin, T. Raudsepp, P. K. Riggs, K. J. Ryan, J. M. Sturino, H. Zhou

Genetics
(GENE)

105. Perspectives in Genetics: Past, Present and Future. (2-0). Credit 2. I

Impact of genetics on science and society: historical and continuing development of genetics and its contributions to agricultural, biological, medical, physical and social studies. Prerequisite: Freshman or sophomore classification or approval of instructor.

285. Directed Studies. Credit 1 to 4.

Introduction to laboratory research. Prerequisite: Freshman or sophomore classification in genetics or approval of instructor.

289. Special Topics in… Credit 1 to 4.

Selected topics in an identified area of genetics. May be repeated for credit. Prerequisites: Freshman or sophomore classification in genetics; approval of instructor.

291. Research. Credit 1 to 4.

Research conducted under the direction of faculty member in genetics. May be repeated 2 times for credit. Prerequisites: Freshman or sophomore classification and approval of instructor.

301. Comprehensive Genetics. (3-3). Credit 4. I, II, S

Survey of the fundamental principles of genetics: Physical basis of Mendelian inheritance, expression and interaction of genes, linkage, sex linkage, biochemical nature of genetic material and mutation. Credit will not be given for more than one of GENE 301, 302, 315 or 320. Not open to biochemistry or genetics majors. Prerequisite: BIOL 112.

302. Principles of Genetics. (3-3). Credit 4. I, II

Mechanisms of inheritance, stressing the conservation of fundamental genetic processes throughout evolution, from bacteria to humans; mutations and phenotypes, Mendelian genetics, population genetics and evolution, and complex inheritance. Course designed for biochemistry, genetics and all majors in biology. Credit will not be given for more than one of GENE 301, 302, 315 and 320. Prerequisite: BIOL 112.

310. Principles of Heredity. (3-0). Credit 3. I, II

Basic principles of classical genetics, molecular genetics, mutation theory and genetic engineering; emphasis on humans and society. Not open to biochemistry and genetics majors. Prerequisite: Junior classification.

315. Genetics of Plants. (3-0). Credit 3.

Fundamental genetic principles as applied to plants: transmission, replication, expression and interaction of genes; linkage, recombination and mapping; chromosomal and gene mutation; behavior of genes in populations; selection, mating systems, cytoplasmic inheritance; molecular analysis and manipulation of genes and gene products; genetically modified plants. Not open to biochemistry or genetics majors. Credit will not be given for more than one of GENE 301, 302, 315 or 320. Prerequisite: BIOL 101 or BIOL 111.

320. Biomedical Genetics. (3-0). Credit 3. I, II

Fundamental genetic principles as applied to biomedical science; Mendelian inheritance, linkage and genetic mapping, mutagenesis and pedigree analysis; molecular basis of gene function and inherited disease; gene therapy and genetic counseling. Credit will not be given for more than one of GENE 301, 302, 315 or 320. Prerequisite: BIMS major with a minimum overall 2.5 TAMU GPA. Cross-listed with BIMS 320.

404. Plant Breeding. (2-2). Credit 3.

Application of genetics and other sciences to the breeding and improvement of horticultural crops; methods and special techniques employed. Prerequisite: GENE 301. Cross-listed with HORT 404. Credit cannot be given for HORT 404 and SCSC 304.

405. Mammalian Genetics. (3-0). Credit 3.

Comparative mammalian genetic systems with emphasis on laboratory animals; organization and expression of mammalian genes; development and use of genetically defined animals in biomedical and genetic research. Prerequisite: GENE 302. Cross-listed with BIMS 405.

406. Bacterial Genetics. (3-0). Credit 3.

A problem oriented course surveying the manipulation and mechanisms of genetic systems in bacteria; recombination, gene structure and regulation of bacterial genes, plasmids and phages. Prerequisites: GENE 302; BIOL 351. Cross-listed with BIOL 406.

411. Biotechnology for Crop Improvement. (3-0). Credit 3.

Use of biotechnology to improve agricultural, horticultural and forest crops; techniques and methods used and case studies where biotechnology has been used to alter traits such as pathogen resistance, protein or oil consumption, ripening, fertility and wood properties. Prerequisite: BIOL 111 or equivalent. Cross-listed with MEPS 411.

412. Population and Ecological Genetics. (3-0). Credit 3. I, II

Concepts of population genetics: dynamics of natural populations with emphasis on ecological interactions. Prerequisite: GENE 302.

420. Bioethics. (3-0). Credit 3. II

The application of ethical theory to the use of modern genetics and biochemistry stressing the social implications of genetic engineering, agricultural manipulation and biotechnology. Prerequisites: GENE 302; BICH 410 or 440.

421. Advanced Human Genetics. (3-0). Credit 3.

A rigorous, analytical approach to genetic analysis of humans including diagnosis and management of genetic disease in humans; transmission of genes in human populations; human cytogenetics; the structure of human genes; human gene mapping; molecular analysis of genetic disease; genetics screening and counseling. Prerequisites: GENE 302; BICH 410 or 440. Cross-listed with BIMS 421.

431. Molecular Genetics. (3-0). Credit 3. I, II

Molecular basis for inheritance: gene structure and function, chromosomal organization, replication and repair of DNA, transcription and translation, the genetic code, regulation of gene expression, genetic differentiation and genetic manipulations. Prerequisites: BICH 410 or 440; GENE 301 or 302 or 320. Cross-listed with BICH 431.

432. Laboratory in Molecular Genetics. (0-6). Credit 2. II

Laboratory for molecular genetics providing technical experience with tools of molecular biology. Prerequisite: GENE 431 or concurrent registration. Cross-listed with BICH 432.

450. Recombinant DNA and Biotechnology. (3-0). Credit 3. I, II

Basic genetic engineering techniques; cloning with plasmid, lambda, cosmid and M13 vectors; gene libraries; DNA sequencing and mutagenesis; PCR; eucaryotic expression with yeast, baculovirus and mammalian vectors; transgenic animals and plants; gene therapy; monoclonal antibodies; bioremediation. Prerequisites: BICH 431 or GENE 431 or concurrent registration; BICH 411 or 441 or concurrent registration.

452. Modifying Mammalian Genomes for Biomedical Research. (3-0). Credit 3.

Review advances in the production of transgenic animals, the manipulation of embryonic stem cells for transgenics and therapeutics, the modification of specific genes in mammalian species by homologous recombination and RNA interference; special emphasis on genetic manipulation of cells and animals for biomedical research, stem-cell and gene therapy. Prerequisite: GENE 302. Cross-listed with BIMS 452.

481. Genetics I Seminar. (1-0). Credit 1. I

Seminar topics on recent developments in genetics. Prerequisites: GENE 302; GENE 431 or concurrent registration; senior classification or approval of instructor.

482. Genetics II Seminar. (1-0). Credit 1. II

Student preparation and presentation of pertinent genetics topics. Prerequisites: GENE 481; senior classification or approval of instructor.

485. Directed Studies. Credit 1 to 4 each semester. I, II, S

Directed study in genetics not included in established courses. Prerequisites: Junior or senior classification; approval of instructor and department head.

489. Special Topics in… Credit 1 to 4. I, II, S

Selected topics in an identified area of genetics. May be repeated for credit. Prerequisite: Approval of instructor.

491. Research. Credit 1 to 4 each semester.

Laboratory research supervised by a faculty member. Registration in multiple sections of this course are possible within a given semester provided that the per semester credit hour limit is not exceeded. Prerequisites: Junior or senior classification in genetics; approval of instructor and department head.