MSCI - Medical Sciences

MSCI 601 Contemporary Topics in Advanced Cell Biology I

Credits 5. 5 Lecture Hours.

Advanced cell and molecular biology course examining the molecular basis of cellular functions relevant to human health. Specific topics will vary but the course will focus on the basic structures, functions and properties of proteins, nucleic acids and lipids. There will be an emphasis on recent developments and the primary literature.
Prerequisites: BIOL 413, BICH 303 or equivalent.

MSCI 602 Contemporary Topics in Advanced Cell Biology II

Credits 5. 5 Lecture Hours.

Continuation of MSCI 601. Advanced cell and molecular biology course examining the molecular basis of cellular functions relevant to human health. Specific topics will vary but the course will focus on emergent properties of complex cellular systems. There will be an emphasis on recent developments and the primary literature.
Prerequisites: MSCI 601 or equivalent.

MSCI 606 Application of Clinical Quality Improvement and Patient Safety Principles

Credits 4. 4 Lecture Hours.

This interdisciplinary “case-based” learning course introduces the student to principles of patient safety and quality improvement and then provides the opportunity to apply these principles to clinical situations. Students engage in discussion and case reviews that promote critical thinking skills, team communication, recognition of systems issues impacting patient care and current issues impacting clinical quality improvement and patient safety.

MSCI 607 Life Science Entrepreneurship

Credits 3. 3 Lecture Hours.

Independent study designed as an introduction and overview of the commercialization process involved in moving a research discovery from the bench to the market.

MSCI 608 Development and Commercialization of Human Therapeutics

Credits 2. 2 Lecture Hours.

Survey the principles and concepts of commercializing a human pharmaceutical drug within the context of a startup biotechnology; emphasis on the issues and concepts encountered in either academic or industrial careers in moving potential pharmaceutical drug towards approved therapeutic.

MSCI 609 Responsible Conduct of Research

Credit 1. 1 Lecture Hour.

Responsible Conduct of Research (RCR) is defined by NIH as the practice of scientific investigation with integrity. It involves the awareness and application of established professional norms and ethical principles in the performance of all activities related to scientific research. Responsible conduct of research is an essential component of research training. This course is designed as a survey of basic topics that trainees will need to understand as they enter into the practice of research. The course will utilize outside reading assignments, online modules, class presentation and discussion of cases associated with each topic.

MSCI 610 Pathogenesis of Human Disease

Credits 1 to 4. 1 to 4 Lecture Hours.

Molecular mechanisms of human disease processes; the main goal of the course is to provide students with an understanding of basic disease processes such as cardiovascular disease, cancer, inflammatory disease, AIDS, tuberculosis, diabetes, Alzheimer’s disease and spinal cord injury.

MSCI 611 Experimental Design for Biomedical Science

Credits 3. 3 Lecture Hours.

Students learn about the principles of experimental design. By the end of the course, the student should be able to incorporate appropriate design features into their own experiments and critically evaluate the experimental literature for design flaws and inappropriate use of statistics.
Prerequisite: Undergraduate or graduate statistics 3 hours.

MSCI 612 Current Topics in Cell Signaling

Credits 3. 3 Lecture Hours.

The course provides an overview of intracellular signal transduction pathways utilized by various classes of growth factor, cytokine, integrin and G-protein coupled receptors. The course also will provide a clear understanding of the importance of these pathways in regulating cell growth, differentiation, apoptosis and other cellular processes, both under normal physiologic conditions as well as diseases.

MSCI 620 The Scientific Basis of Medicine

Credit 1. 1 Other Hour.

Journal club in which recent research papers relevant to medicine are presented by students and discussed by students and faculty. May be taken four times for credit.

MSCI 630 Pathogenesis of Human Disease

Credits 4. 4 Lecture Hours.

Upon completion of this course, the student will be able to recognize and describe the molecular events responsible for various human diseases. The student will be able to differentiate between various types of diseases and independently assemble a concise presentation on a particular disease topic.

MSCI 631 Pathogenesis of Human Disease – Introduction to Inflammation and Human Disease

Credit 1. 1 Lecture Hour.

Upon completion of this course, the student will be able to recognize and describe the molecular events that occur in inflammation, along with innate and adaptive immune responses. Various inflammatory mediators and signaling events will be discussed in the context of inflammation alongside a general introduction to immune responses. A relevant clinical condition will be discussed to reinforce these concepts.

MSCI 632 Pathogenesis of Human Disease – Cardiovascular Disease

Credit 1. 1 Lecture Hour.

Upon completion of this course, the student will be able to recognize and describe the molecular events that occur in the most frequent cardiovascular diseases affection the Western world, including coronary artery disease, ischemia, atherosclerosis, myocardial infarction, stroke, hypertension, cardiac hypertrophy, and heart failure.

MSCI 633 Pathogenesis of Human Disease – Infectious Disease

Credit 1. 1 Lecture Hour.

Upon completion of this course, the student will be able to recognize and describe the molecular events that occur in response to bacterial and viral pathogens responsible for respiratory, gastrointestinal and urogenital disease, as well as AIDS and other viral infections.

MSCI 634 Pathogenesis of Human Disease – Neurodegenerative and Genetic Disease

Credit 1. 1 Lecture Hour.

Upon completion of this course, the student will be able to recognize and describe the molecular events that occur in Alzheimer's, Parkinson's neurodegenerative disease in women, Muscular Dystrophy, neoplasia, tumor metastasis and dissemination, and breast cancer.

MSCI 635 Basic Immunology

Credits 2. 2 Lecture Hours.

This course is designed to give students a basic and current understanding of the immune system. The course consists of lectures as well as presentations by a student (or teams of students) where the student/team describes the accepted paradigm for the lecture topic; identifies and discusses the historical references for the paradigm; and reviews and discusses current publications in the field, with the goal of determining if current data and research remain consistent or are inconsistent with the accepted paradigm in that area of immunology.

MSCI 636 Intermediate and Translational Immunology

Credits 2. 2 Lecture Hours.

This course is designed to build on students' basic understanding of the immune system. Course consists of lectures on a clinical problem/disease by the director/guest lecturer; followed by student presentations describing how the immune system may impact the disease of interest, either positively or negatively, and a group discussion on how to modify clinical outcomes with immune-based interventions that translate basic understanding to clinical treatments. All participants will review and discuss current publications in the field.

MSCI 681 Seminar

Credit 1. 1 Lecture Hour.

Focus will be on critical scientific thinking. Emphasis placed on oral communications, scientific writing and grant preparation.
Prerequisite: Approval of instructor.

MSCI 685 Directed Studies

Credits 1 to 6. 1 to 6 Lecture Hours.

Limited investigation in fields other than those chosen for thesis or dissertation.
Prerequisite: Approval of instructor.

MSCI 687 Professionalism and Ethics

Credit 1. 1 Lecture Hour.

Students learn about professionalism and ethics in the medical sciences.

MSCI 689 Special Topics

Credits 1 to 4. 1 to 4 Lecture Hours.

Selected topics in an identified area of medical sciences. May be repeated for credit when topics vary.
Prerequisite: Approval of instructor.

MSCI 690 Theory of Medical Science Research

Credits 2. 2 Lecture Hours.

Design of research experiments in various fields of medical sciences; evaluation of end results with the aid of examples taken from current scientific literature.
Prerequisites: Approval of instructor.

MSCI 691 Research Credit: Medical Science

Credits 1 to 15. 1 to 15 Lab Hours.

Research for thesis or dissertation.
Prerequisites: Approval of supervisory professor in chosen field.

MSCI 695 Frontiers in Medical Science Research

Credits 2. 2 Lecture Hours.

Present status of research in a variety of significant medical sciences fields. Content depends on the availability of visiting lecturers who are selected because of distinguished international recognition in their field of research. May be repeated for credit.
Prerequisite: Graduate classification.

MSCI 920 The Scientific Basis of Medicine

Credit 1. 1 Other Hour.

This course is a journal club in which recent research papers relevant to medicine are presented by students and discussed by students and faculty. May be repeated for credit four times.