BICH - Biochemistry (BICH)

BICH 101/GENE 101 Perspectives in Biochemistry and Genetics

Credit 1. 1 Lecture Hour.

Introduction to biochemistry and genetics and their relationship to the biological, biophysical and chemical sciences.
Prerequisite: Biochemistry and genetics major or approval of instructor.
Cross Listing: GENE 101/BICH 101.

BICH 281 Seminar in Biochemical Research

Credit 1. 1 Lecture Hour.

Round table discussions with visiting seminar speakers; review current literature; topics including cutting edge research in biochemistry.
Prerequisites: BICH 107 and freshman or sophomore classification in biochemistry or approval of instructor.

BICH 285 Directed Studies

Credits 1 to 4. 1 to 4 Other Hours.

Introduction to laboratory research.
Prerequisite: Freshman or sophomore classification in biochemistry or approval of instructor.

BICH 289 Special Topics in...

Credits 1 to 4. 1 to 4 Lecture Hours.

Selected topics in an identified area of biochemistry. May be repeated for credit.
Prerequisite: Freshman or sophomore classification in biochemistry or approval of instructor.

BICH 291 Research

Credits 1 to 4. 1 to 4 Other Hours.

Research conducted under the direction of faculty member in Biochemistry. May be repeated 2 times for credit.
Prerequisites: Freshman or sophomore classification and approval of instructor; biochemistry majors only.

BICH 303 Elements of Biological Chemistry

Credits 3. 3 Lecture Hours.

Survey of the biochemical sciences designed for the non-biochemistry major; introduction to the chemistry and metabolism of biologically important molecules, the biochemical basis of life processes, cellular metabolism and regulation. Students requiring biochemistry in greater depth should register for BICH 410 and BICH 411. Not open to biochemistry majors.
Prerequisite: CHEM 222 or equivalent.

BICH 404 Biochemical Calculations

Credits 2. 2 Lecture Hours.

Quantitative and computational approaches to biochemical problems.
Prerequisites: BICH 440 or registration therein; junior or senior classification.

BICH 407 Horizons in Biological Chemistry II

Credit 1. 1 Lecture Hour.

Application of formal classroom instruction; applied view of biochemical concepts; use of biochemical principles to ascertain, evaluate, and make judgments on research information. May be taken five times.
Prerequisite: BICH 411 or BICH 441.

BICH 410 Comprehensive Biochemistry I

Credits 3. 3 Lecture Hours. 1 Lab Hour.

Structure, function and chemistry of proteins and carbohydrates; kinetics, mechanisms and regulation of enzymes; metabolism of carbohydrates. Not open to biochemistry or genetics majors.
Prerequisite: CHEM 228 or approval of instructor.

BICH 411 Comprehensive Biochemistry II

Credits 3. 3 Lecture Hours. 1 Lab Hour.

A continuation of BICH 410. Structure, function, chemistry and metabolism of lipids and nucleic acids; cellular metabolism viewed from the standpoint of energetics and control mechanisms; interrelationships of metabolic pathways. Not open to biochemistry or genetics majors.
Prerequisite: BICH 410.

BICH 412 Biochemistry Laboratory I

Credit 1. 3 Lab Hours.

Selected methods used to identify, isolate, purify and characterize biomolecules. Not open to biochemistry or genetics majors.
Prerequisite: BICH 410 or registration therein.

BICH 414 Biochemical Techniques I

Credits 2. 6 Lab Hours.

Techniques currently used in biochemistry such as spectrophotometry, column chromatography (gel filtration, ion exchange) electrophoresis and immunoelectrophoresis, performed in purification of proteins, enzymes and nucleic acids. For majors in biochemistry, genetics, molecular and cell biology and microbiology.
Prerequisite: BICH 440.

BICH 419/GENE 419 Computational Techniques for Evolutionary Analysis

Credits 3. 3 Lecture Hours.

Computational techniques for studying evolution; algorithms for construction and analysis of evolutionary relationships.
Prerequisite: Junior or senior classification or approval of instructor.
Cross Listing: GENE 419/BICH 419.

BICH 431/GENE 431 Molecular Genetics

Credits 3. 3 Lecture Hours.

Molecular basis for inheritance: gene structure and function, chromosomal organization, replication and repair of DNA, transcription and translation, the genetic code, regulation of gene expression, genetic differentiation and genetic manipulations.
Prerequisites: BICH 410 or BICH 440; GENE 301 or GENE 302 or GENE 320/BIMS 320.
Cross Listing: GENE 431/BICH 431.

BICH 432/GENE 432 Laboratory in Molecular Genetics

Credits 2. 6 Lab Hours.

Laboratory for molecular genetics providing technical experience with tools of molecular biology.
Prerequisite: GENE 301, GENE 302 or GENE 320/BIMS 320; BICH 410 or BICH 440.
Cross Listing: GENE 432/BICH 432.

BICH 440 Biochemistry I

Credits 3. 3 Lecture Hours.

Rigorous treatment of the structure, function and chemistry of proteins and carbohydrates; kinetics, mechanisms and regulation of enzymes; metabolism of carbohydrates. Course designed for biochemistry and genetics majors and honors students only.
Prerequisite: CHEM 228 or approval of instructor.

BICH 441 Biochemistry II

Credits 3. 3 Lecture Hours.

Continuation of BICH 440; structure, function, chemistry and metabolism of lipids and nucleic acids, cellular metabolism viewed from the standpoint of energetics and control mechanisms; interrelationships of metabolic pathways. Course designed for biochemistry and genetics majors and honors students only.
Prerequisite: BICH 440.

BICH 450/BIOL 450 Genomics

Credits 4. 3 Lecture Hours. 3 Lab Hours.

The study of genomic data includes consideration of the logic behind the most important genomic approaches, as well as their capabilities and limitations in investigating biological processes; the science of accessing and manipulating genomic data; and practical applications, including development of an hypotheses-driven datamining experiment.
Prerequisites: BIOL 213, GENE 301 or GENE 302, BICH 431/GENE 431 or GENE 431/BICH 431, or BIOL 351; junior or senior classification or approval of instructor.
Cross Listing: BIOL 450/BICH 450.

BICH 460 Genome Annotation with Ontologies

Credit 1. 2 Lab Hours.

Use of ontologies as structured controlled vocabularies for the organization of biological data; annotation based on critical reading of the scientific literature. May be taken two times for credit.
Prerequisite: Junior or senior classification or approval of instructor.

BICH 461 Advanced Genome Annotation with Ontologies

Credit 1. 2 Lab Hours.

Advanced topics in functional annotation using ontologies; usage issues and quality control for ontologies and annotations; mentoring annotation activities from BICH 460 and evaluation of annotations. May be taken three times for credit.
Prerequisite: BICH 460; junior or senior classification or approval of instructor.

BICH 464 Bacteriophage Genomics

Credits 3. 1 Lecture Hour. 6 Lab Hours.

Examines the latest technologies in genomic analysis by sequencing and annotating the genomes of novel bacterial viruses (phage); generates real data which will be submitted to the NIH/NCBI public database; includes phage biology and potential uses.
Prerequisites: GENE 302; BIOL 351 or concurrent enrollment; approval of instructor.

BICH 485 Directed Studies

Credits 1 to 4. 1 to 4 Other Hours.

Directed study in biochemistry not included in established courses.
Prerequisites: Junior or senior classification; approval of instructor and department head.

BICH 489 Special Topics in...

Credits 1 to 4. 1 to 4 Lecture Hours. 0 to 4 Lab Hours.

Selected topics in an identified area of biochemistry, biophysics or nutrition. May be repeated for credit.
Prerequisite: Junior or senior classification in life or physical sciences.

BICH 491 Research

Credits 1 to 4. 1 to 4 Other Hours.

Registration in multiple sections of this course are possible within a given semester provided that the per semester credit hour limit is not exceeded.
Prerequisite: Biochemistry major.