Department of Veterinary Physiology and Pharmacology

http://vetmed.tamu.edu/vtpp

Head: Larry J. Suva

The Department of Veterinary Physiology and Pharmacology is the only department of its kind in the state of Texas, and has a rich tradition of excellence in education, research and outreach with an emphasis on both veterinary and human medicine.  The department houses the Michael E. DeBakey Institute for Comparative Cardiovascular Science and Biomedical Devices, the Reproductive Sciences Laboratory, the Interdisciplinary Faculty of Toxicology, and the newest addition, the Center for Cell and Organ Biotechnology.

The primary research focus areas within the department include cardiovascular sciences, reproductive sciences, regenerative medicine, pharmacology and toxicology.  The department has a well-funded, well-published, and internationally renowned faculty who have extensive research collaborations with the Colleges of Agriculture & Life Sciences, Science, Engineering, Education & Human Development, the Texas A&M University Health Science Center, the School of Public Health, Texas A&M AgriLife Research and the Texas A&M Engineering Experiment Station. Our faculty have achieved national and international recognition in teaching, research and service.

Many departmental faculty members serve on university intercollegiate faculties, providing the basis for a strong graduate education experience. Graduate programs leading to the Master of Science (MS) and Doctor of Philosophy (PhD) degrees in Biomedical Sciences or Toxicology are designed to prepare the graduate for research, teaching and other related areas. Faculty specialty areas include cardiovascular sciences, reproductive sciences, regenerative medicine, pharmacology and toxicology.

VTPP 605 Systemic Veterinary Physiology I

Credits 5. 5 Lecture Hours.

Aspects of cellular physiology, physiology of excitable membranes, physiology of body fluids, neurophysiology, and the physiology of smooth, cardiac and skeletal muscle; provides a basic understanding of mammalian physiology essential as a framework for advanced graduate studies.
Prerequisite: Graduate classification.

VTPP 606 Systemic Veterinary Physiology II

Credits 5. 5 Lecture Hours.

In-depth study covering cardiovascular, respiratory, renal physiology, gastrointestinal and endocrine physiology; provides a basic understanding of mammalian physiology essential as a framework for advanced graduate studies.
Prerequisite: VTPP 605.

VTPP 610 Physiology I

Credits 6. 5 Lecture Hours. 2 Lab Hours.

Introduction to physiology: cell physiology, cell signaling, cell cycle, body fluids, translocation of materials, membrane potentials, neurophysiology, autonomic nervous system, thermoregulation, cardiovascular, and muscle physiology.
Prerequisites: Enrollment in MS/PhD program in Veterinary Physiology and Pharmacology; approval of instructor.

VTPP 612 Physiology II

Credits 6. 5 Lecture Hours. 2 Lab Hours.

Blood and lymph, respiration, renal physiology, and acid-based balance, gastrointestinal physiology, metabolism, endocrinology, and reproduction.
Prerequisites: Enrollment in MS/PhD program in Veterinary Physiology and Pharmacology; approval of instructor.

VTPP 623 Biomedical Physiology I

Credits 4. 3 Lecture Hours. 2 Lab Hours.

Physiological principles, review of cellular physiology, and development of an understanding of the nervous system and muscle, cardiovascular, and respiratory physiology; clinical applications related to organ systems.
Prerequisites: Graduate classification; BICH 410 and VIBS 305 recommended.

VTPP 624/VIBS 624 Endocrinology

Credits 4. 3 Lecture Hours. 3 Lab Hours.

Neuroendocrine control of puberty menstruation, ovulation, pregnancy, labor, lactation, female reproductive cycles, male reproductive functions, thyroid and parathyroid, adrenal and kidney, diabetes, obesity, sleep, memory, learning and aging, and their endocrine disorders; overview on biosynthesis, transport and signaling of peptide and neuropeptide hormones, steroids and prostaglandins.
Prerequisite: Graduate classification.
Cross Listing: VIBS 624/VTPP 624.

VTPP 625 Pharmacology

Credits 3. 3 Lecture Hours.

Introduction to pharmacokinetics and pharmacodynamics; survey of major pharmaceutical classes; uses, mechanisms of action and adverse reactions of selected agents.
Prerequisites: Graduate classification; VTPP 423 or approval of instructor.

VTPP 627 Biomedical Physiology II

Credits 3. 3 Lecture Hours.

Continuation of VTPP 623 Fluid balance and acid-base balance; development of an understanding of renal, gastrointestinal, endocrine and reproductive physiology using human and other mammalian models; clinical applications related to organ systems.
Prerequisites: Graduate classification; VTPP 623.

VTPP 628 Pharmacology I

Credits 5. 4 Lecture Hours. 2 Lab Hours.

Pharmacokinetics, pharmacodynamics, CNS pharmacology, autonomic pharmacology, antineoplastic agents, immunopharmacology, recombinant products, fluid and electrolyte therapy, diuretics, pharmacology of the integument.
Prerequisite: Approval of instructor.

VTPP 629 Pharmacology II

Credits 3. 2 Lecture Hours. 2 Lab Hours.

Antimicrobials, endocrine pharmacology, eicosanoids, anti-inflammatory agents, respiratory pharmacology, anticoagulants and hematinics, GI pharmacology, cardiovascular pharmacology.
Prerequisite: Approval of instructor.

VTPP 630 Pharmacology/Toxicology

Credits 3. 2 Lecture Hours. 2 Lab Hours.

Management and treatment of toxicosis, antidotal pharmacology, toxic plants, mycotoxins, chemical toxicants, metals, euthanasia.
Prerequisite: Approval of instructor.

VTPP 634 Physiology for Bioengineers I

Credits 4. 3 Lecture Hours. 3 Lab Hours.

Cellular anatomy, cellular physiology and biochemistry; systems analysis of digestive, endocrine and musculoskeletal system function including information related to gross anatomy, histology and disease states; quantitative aspects of physiology and engineering applications to clinical medicine.
Prerequisite: Biomedical Engineering major or approval of instructor.

VTPP 635 Physiology for Bioengineers II

Credits 4. 3 Lecture Hours. 3 Lab Hours.

A systems analysis of nervous, cardiovascular, respiratory and urinary function including information related to gross anatomy, histology and disease states; quantitative aspects of physiology and engineering applications to clinical medicine.
Prerequisite: VTPP 634.

VTPP 638 Analysis of Genomic Signals

Credits 3. 2 Lecture Hours. 2 Lab Hours.

Overview of current high throughput technology for data acquisition and analysis of genomic signals (e.g., mRNA or proteins); emphasis on microarray technology, methods for analyzing microarray data, and approaches to model the underlying phenomena from the systems biology perspective.
Prerequisites: BIOL 451 or GENE 320/BIMS 320/BIMS 320/GENE 320 or equivalent; STAT 651 or equivalent; or approval of instructor.

VTPP 639 Non-Coding RNAs

Credits 3. 3 Lecture Hours.

Roles of non-coding RNAs in regulating gene expression for physiological functions, development and diseases; includes a brief history of the field, various categories and definitions of non-coding RNAs, research methodologies and animal models, and break-through advances in clinical applications.
Prerequisite: Approval of instructor.

VTPP 650 Stem Cell Biology

Credits 3. 3 Lecture Hours.

Wide-range of topics related to stem cells and tissue engineering, including a brief history of the field, various categories and definitions of stem cells, research methodologies and animal models, as well as break-through advances in the area of engineered stem cells.
Prerequisite: Approval of instructor.

VTPP 651 Epigenetics & Systems Physiology

Credits 3. 3 Lecture Hours.

Epigenetics & Systems Physiology. Journal club format focusing on epigenetic regulation of physiological systems; assignment of papers from primary literature and weekly oral presentations detailing opinions on research; emphasis on fundamental concepts in epigenetics, physiology and the molecular techniques employed to address research hypotheses, discussions of scientific ethics and fraud.
Prerequisite: Graduate classification.

VTPP 652 Fetal and Embryo Physiology

Credits 3. 3 Lecture Hours.

Introduction to the physiologic processes driving embryonic development and pregnancy; focus on embryo implantation, establishment of the placenta, development of the fetal circulatory systems and the molecular processes governing embryo differentiation and development; special emphasis on the major organ systems affected by pediatric disease and on the actions of teratogens.
Prerequisites: Graduate classification.

VTPP 653 Endocrinology

Credits 4. 3 Lecture Hours. 3 Lab Hours.

Physiology, biochemistry and pharmacology of the endocrines. Laboratory emphasizes a number of classical experiments with clinical application.
Prerequisite: Approval of instructor.

VTPP 654 Molecular Endocrinology

Credits 3. 3 Lecture Hours.

Structure-function relationships of hormones, their receptors and biologic activities.
Prerequisites: VTPP 653 or BIOL 649 and BICH 410 or equivalent or approval of instructor.

VTPP 655 Vascular Physiology

Credits 4. 4 Lecture Hours.

Structure and function of blood vessels and vascular beds; molecular and cell biology of endothelium and vascular smooth muscle; microcirculation; capillary exchange; regulation of blood flow by local, neural and humoral signals.
Prerequisite: MPHY 901 or approval of department head.

VTPP 656 Physiology of the Heart

Credits 4. 4 Lecture Hours.

Structure and function of the heart; molecular and cell biology of cardiac myocytes; electrophysiology of myocardium, pacemaker cells and conducting tissue; cardiac mechanics; control of cardiac performance; coronary circulation.
Prerequisite: MPHY 901 or MPHY 604 or approval of department head.

VTPP 657 Cardiovascular Physiology

Credits 4. 3 Lecture Hours. 3 Lab Hours.

Physiological considerations of the circulatory system including general and integrative aspects of the heart and blood vessels.
Prerequisites: Approval of instructor.

VTPP 659 Gamete and Embryo Physiology

Credits 3. 2 Lecture Hours. 2 Lab Hours.

Physiology of gametes and preimplantation embryos in livestock and laboratory animals; oocyte growth and maturation in-vivo and in-vitro, fertilization in-vivo and in-vitro, embryo transfer, cryopreservation, nuclear transfer, chimera formation, gene transfer.

VTPP 667 Current Topics in Pharmacology

Credits 3. 3 Lecture Hours.

Discussions of literature regarding topics of current research interest; physiochemical or physiologic effects of drugs at sites from molecular to whole body.
Prerequisite: Approval of instructor.

VTPP 673 Metabolic and Detoxication Mechanisms

Credits 3. 3 Lecture Hours.

Fate of foreign compounds; their inhibitory and antagonistic action toward normal metabolic processes of the animal body.
Prerequisites: BICH 603; approval of instructor and department head.

VTPP 675 Industrial and Environmental Toxicology

Credits 3. 3 Lecture Hours.

Fundamentals of toxicology and risk assessment; effects of selected classes of hazardous chemicals encountered in the workplace or environment on human health will be considered.
Prerequisite: Approval of instructor.

VTPP 676 Genetic and Molecular Toxicology

Credits 3. 3 Lecture Hours.

Mechanisms of toxicant-induced target organ toxicity with emphasis on molecular control of mammalian and cell growth differentiation.
Prerequisite: Graduate course in cell biology and biochemistry.

VTPP 677 Fluorescence Detection: Steady State, Time Resolved and Imaging

Credits 4. 4 Lecture Hours.

Fluorescence spectroscopy and confocal/multiphoton microscopy in research; intro of pharmacology, life science, and physical science students to fluorophores, anisotropy, ligand binding, energy transfer, cytometry, lifetime imaging, correlation spectroscopy, immunocytochemistry, and image analysis with an emphasis on instrumental/sample artifacts, fluorescence application, literature evaluation, and communication of rationales to other scientists.
Prerequisite: General chemistry and biology course.

VTPP 681 Seminar

Credit 1. 1 Lecture Hour.

Review and discussion of current scientific work in physiology and related subjects.
Prerequisite: Approval of department head.

VTPP 685 Directed Studies

Credits 1 to 4. 1 to 4 Other Hours.

Problems in physiology, pharmacology or toxicology.
Prerequisite: Approval of instructor.

VTPP 689 Special Topics in...

Credits 1 to 4. 1 to 4 Lecture Hours. 0 to 4 Lab Hours.

Selected topics in an identified area of veterinary physiology and pharmacology. May be repeated for credit.
Prerequisite: Approval of instructor.

VTPP 690 Theory of Research

Credits 3. 3 Lecture Hours.

Theory and design of research related to current biomedical problems especially those involving study of animal disease; philosophical perspectives underlying historical advances in research pertaining to the study, prevention and treatment of disease.
Prerequisite: Graduate classification.
Cross Listing: VIBS 690 and VPAT 690.

VTPP 691 Research

Credits 1 to 23. 1 to 23 Other Hours.

Original investigations in veterinary physiology, pharmacology or toxicology to be submitted by writing of thesis or dissertation as partial fulfillment for MS or PhD degree.
Prerequisite: Approval of department head.

VTPP 910 Physiology I

Credits 6. 5 Lecture Hours. 2 Lab Hours.

Introduction to physiology: cell physiology, cell signaling, cell cycle, body fluids, translocation of materials, membrane potentials, neurophysiology, autonomic nervous system, thermoregulation, cardiovascular, and muscle physiology.
Prerequisite: Enrollment in first year of professional curriculum.

VTPP 912 Physiology II

Credits 6. 5 Lecture Hours. 2 Lab Hours.

Blood and lymph, respiration, renal physiology, and acid-base balance, gastrointestinal physiology, metabolism, endocrinology, and reproduction.
Prerequisite: Enrollment in the first year of professional curriculum.

VTPP 924 Pharmacology/Toxicology I

Credits 5. 4 Lecture Hours. 2 Lab Hours.

Pharmacokinetics, pharmacodynamics, CNS pharmacology, autonomic pharmacology, antineoplastic agents, immunopharmacology, recombinant products, fluid and electrolyte therapy, diuretics, pharmacology of the integument.
Prerequisite: Enrollment in the second year of professional curriculum.

VTPP 925 Pharmacology/Toxicology II

Credits 3. 5 Lecture Hours. 2 Lab Hours.

Antimicrobials, endocrine pharmacology, eicosanoids, antiinflammatory agents, respiratory pharmacology, anticoagulants and hematinics, GI pharmacology, cardiovascular pharmacology.
Prerequisite: Enrollment in the second year of professional curriculum.

VTPP 926 Pharmacology/Toxicology III

Credits 3. 2 Lecture Hours. 2 Lab Hours.

Management and treatment of toxicoses, antidotal pharmacology, toxic plants, mycotoxins and mycotoxicoses, chemical toxicants, metals, euthanasia.
Prerequisite: Enrollment in the second year of professional curriculum.

VTPP 948 Didactic Elective in Veterinary Physiology and Pharmacology

Credits 1 to 12. 1 to 12 Lecture Hours.

Elective course in physiology and pharmacology for professional students who wish to supplement required curriculum. May be repeated for credit.
Prerequisite: Enrollment in the fourth year of professional curriculum.

VTPP 985 Directed Studies

Credits 1 to 4. 1 to 4 Other Hours.

Directed, individual study of selected problems in physiology, pharmacology or toxicology. May be repeated for credit.
Prerequisite: Approval of instructor and department head.

Bailey, Everett, Professor
Vet Physiology & Pharmacology
DVM, Texas A&M University, 1964

Blue-Mclendon, Alice, Clinical Assistant Professor
Vet Physiology & Pharmacology
BS, Texas A&M University, 1987

Dongaonkar, Ranjeet, Assistant Professor
Vet Physiology & Pharmacology
PHD, Texas A&M University, 2008

Fajt, Virginia, Clinical Associate Professor
Vet Physiology & Pharmacology
PHD, Iowa State University, 2000

Golding, Michael, Associate Professor
Vet Physiology & Pharmacology
PHD, Texas A&M University, 2003

Han, Guichun, Clinical Assistant Professor
Vet Physiology & Pharmacology
PHD, Dalian Medical University, China, 2002

Heaps, Cristine, Associate Professor
Vet Physiology & Pharmacology
PHD, Univeristy of Missouri - Columbia, 1999

Herman, James, Clinical Professor
Vet Physiology & Pharmacology
MS, Texas A&M University, 2001

Hinrichs, Katrin, Professor
Vet Physiology & Pharmacology
PHD, University of Pennsylvania, 1988

Ivanov, Ivan, Clinical Associate Professor
Vet Physiology & Pharmacology
PHD, University of South Florida, 1999

Jones, Daniel, Associate Professor
Vet Physiology & Pharmacology
PHD, University of Guelph, 1976

Kraemer, Duane, Senior Professor
Vet Physiology & Pharmacology
PHD, Agricultural & Mechanical College (TAMU), 1966

Long, Charles, Associate Professor
Vet Physiology & Pharmacology
PHD, University of Massachusetts - Amherst, 1996

Muneoka, Ken, Professor
Vet Physiology & Pharmacology
PHD, University of California - Irvine, 1983

Newell-Fugate, Anne, Assistant Professor
Vet Physiology & Pharmacology
PHD, University of Illinois-Urbana Champaign, 2012

Quick, Christopher, Professor
Vet Physiology & Pharmacology
PHD, Rutgers University, 1999

Ramadoss, Jayanth, Assistant Professor
Vet Physiology & Pharmacology
PHD, Texas A&M University, 2007

Robles Emmanuelli, Juan, Clinical Assistant Professor
Vet Physiology & Pharmacology
BS, University of Puerto Rico, 2001

Safe, Stephen, Distinguished Professor
Vet Physiology & Pharmacology
PHD, University of Oxford, 1966

Schroeder, Friedhelm, Professor
Vet Physiology & Pharmacology
PHD, Michigan State University, 1974

Stallone, John, Professor
Vet Physiology & Pharmacology
PHD, University of Arizona, 1984

Stewart, Randolph, Clinical Professor
Vet Physiology & Pharmacology
BS, Texas A&M University, 1981

Suva, Larry, Professor
Vet Physiology & Pharmacology
PHD, The University of Melbourne, Australia, 2016

Tian, Yanan, Associate Professor
Vet Physiology & Pharmacology
PHD, Rutgers University, 1993

Washburn, Shannon, Clinical Assistant Professor
Vet Physiology & Pharmacology
BS, Texas A&M University, 1990

Wasser, Jeremy, Associate Professor
Vet Physiology & Pharmacology
PHD, Indiana University, 1985

Westhusin, Mark, Professor
Vet Physiology & Pharmacology
PHD, Texas A&M University, 1986

Zhou, Beiyan, Associate Professor
Vet Physiology & Pharmacology
PHD, Northwestern University, 2004